A health care provider may consider these conditions in the table below when making a diagnosis. We help you fully understand your treatment options and make the choices that are right for your family. Our specialty is treating children’s conditions while helping them grow up to be healthy and productive. Your child may get chemotherapy at our outpatient infusion unit as a day procedure or stay overnight in our Cancer Care Unit. CrossRef. This can damage the body instead of protecting it. Doctors do not know what causes this disease. That can cause pain and swelling, and sometimes it can fracture your arms or legs. Report from the International Registry of the Histiocyte Society. PubMedCrossRef, Zurück zum Zitat Culic S, Jakobson A, Culic V, Kuzmic I, Scukanec-Spoljar M, Primorac D. Etoposide as the basic and interferon-alpha as the maintenance therapy for Langerhans cell histiocytosis: a RTC. See answer, My toddler daughter has been diagnosed with Langerhans cell histiocytosis. Sie können e.Med Radiologie 14 Tage kostenlos testen (keine Print-Zeitschrift enthalten). Zurück zum Zitat Coppes-Zantinga A, Egeler RM. The tissue damage induced by the disease appears to be related to local cytokine release. It could affect your child’s: Regular checkups and timely treatment can help your child live a healthy, active life. Am J Dis Child 1936;51:499–22. Is this true? National Center for Biotechnology Information, Unable to load your collection due to an error, Unable to load your delegates due to an error. 875–906.  |  COVID-19 Vaccines: Updates You Need to Know, Sign Up to Receive Our Free Coroanvirus Newsletter, Liver Cancer: Symptoms, Tests, and Treatments, MRIs and PET and CT scans to get detailed images of your body, Urinalysis to check levels of red and white cells, protein, and sugar in your pee, Parents who were exposed to environmental toxins, like benzene or wood dust, Bone marrow, liver, or lung transplants in very serious cases. Perianal presentation of Langerhans cell histiocytosis in children. Options include: Very rarely, treatment for Langerhans cell histiocytosis includes an infusion of blood-forming stem cells from a healthy donor. Many children get checkups every 3 months. PubMedCrossRef, Zurück zum Zitat Jenson HB, McClain KL, Leach CT, Deng JH, Gao SJ. Zurück zum Zitat Lichtenstein L, Jaffe HL. If the disease is in your spleen, liver, or bone marrow, it’s called a high-risk LCH. Eur J Radiol 2005;55(1):33–40. But in histiocytosis (HIS-tee-oh-sy-TOE-sis), the cells grow so quickly that they build up. In single system disease, Langerhans cell histiocytosis is responsive to local therapy but, in resistant single system disease or in multisystem disease, etoposide is the most effective monochemotherapy. Am J Hematol 2000;64(4):237–41. Our patients receive chemotherapy at our hospital campus in Seattle. Altay MA, Sindel A, Özalp Ö, Kocabalkan B, Özbudak İH, Erdem R, Salim O, Baur DA. In some children with the disease, extra cells build up and damage 1 area or organ in their bodies. J Pediatr 2002;141(3):435–40. Pediatr Blood Cancer 2004;43(1):81–4. For skin problems, doctors may apply medicines right on the skin (topical treatments). See answer, My child had surgery for Langerhans cell histiocytosis. Helmbold P, Hegemann B, Holzhausen HJ, Klapperstück T, Marsch WC. PubMedCrossRef, Zurück zum Zitat Dreyer ZE, Dowell BL, Chen H, Hawkins E, McClain KL. See answer, My daughter was diagnosed with Langerhans cell histiocytosis. At Seattle Children's, we work with many children and families from around the Northwest and beyond.